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Laryngoscope 130 , 1787 (2020)

Cardiovascular complications remain the leading cause of death in hemodialysis patients and account for a substantial proportion of overall mortality in this population (11)

Hypertensions pathogenesis has been linked to several variables, such as inflammation, renin-angiotensin-aldosterone system overexpression, sympathetic nervous system activation, and aberrant G protein-coupled receptor signaling, as shown in Figure 4 (129131)

Quantification of the percentage of cell death in control, MIRO2 KO#1, MIRO2 KO#1-MIRO2-FLAG, MIRO2 KO#1-MIRO2 (R4)-FLAG (p, n = 58 cells for control-N, n = 57 cells for MIRO2 KO-N, n = 55 cells for MIRO2 KO + MIRO2 (R4)-FLAG-N, n = 52 cells for MIRO2 KO#1 + MIRO2-FLAG-N and -HR, n = 49 cells for MIRO2 KO-HR, n = 51 cells for other, three experiments) or control, shITM2C#1, shITM2C#1-ITM2C(RR)-FLAG (q, n = 58 cells for control-N, n = 55 cells for shITM2C-N, n = 56 cells for shITM2C + ITM2C(RR)-FLAG, n = 53 cells for control-HR, n = 54 cells for shITM2C-HR, n = 49 cells for other, three experiments) HeLa cells under N or HR