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All metabolites were normalized with total analyzed cell numbers for analysis
Dyka D, Rodze , Rodze M, Pacholak-Klimas A, Ede G, Sethi S, et al
Four specific conditions qualify for Tier 3 (BMI 27 or higher): (1) prediabetes per American Diabetes Association criteria (typically A1c 5.7 to 6.4 percent, fasting glucose 100 to 125, or 2-hour oral glucose tolerance test 140 to 199), (2) previous heart attack (myocardial infarction), (3) previous stroke, and (4) symptomatic peripheral artery disease
The GI symptom rates nearly doubled when participants skipped the lower starting dose
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