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Inactive state stabilized by the ECD and ECL1/3 In the GLP-1RFab7F38 structure, the saddle-like ECD loop S116-E127 covers the ECL1 helical region Q211-S219 that partially occupies the orthosteric ECD-binding site (Fig

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Human prostate cancer (PCa) cell lines LNCaP and C4-2 were maintained in RPMI 1640 medium supplemented with 10% FBS

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