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Semaglutide is primarily eliminated via proteolytic degradation rather than renal or hepatic excretion, so no dose adjustment is required for mild, moderate, or severe kidney or liver impairment

The biological plausibility was strongGLP-1 RAs reduce inflammation, improve mitochondrial function, and may modulate pathways involved in neuronal survival

federal research data in which people were asked about their GLP-1 prescriptions

Some patients notice reduced appetite within the first 12 weeks of treatment

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