Similar results were seen in the non-inferiority HARMONY 7 trial, which compared liraglutide versus albiglutide [46]
This drop in Basal Metabolic Rate (BMR) means the calorie deficit that helped you shed pounds early in your GLP-1 journey might no longer be enough to keep the weight coming off
It stimulates insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated, which reduces the risk of hypoglycaemia compared to some other diabetes medications
[52] Clinical trials shown that GLP-1 receptor agonists improve menstrual regularity , decrease body weight and central adiposity, increase sex hormone-binding globulin levels , and lower free testosterone in overweight and obese women with PCOS
Shao W, Chen R, Lin G, Ran K, Zhang Y, Yang J