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Interleukins (mainly IL-1 and IL-6), interferon- (IFN- ) and tumour necrosis factor (TNF)- , produced by immune cells, endothelial cells, platelets and fibroblasts are associated with atherosclerosis onset and progression
use cautiously in patients with gout [16] [25] Myopathy risk : When combined with statins, increased risk of muscle symptoms requires monitoring Glucose effects : Dose-dependent increases in blood glucose and A1c Monitoring recommendations: Glucose monitoring is paramount, particularly during the first few weeks after initiating or adjusting either medication
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Drugs 79 (9), 10231029
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