After 4 weeks of treatment, the average weight gain was: 0.5 lb (0.2 kg) in adults 2 lb (0.9 kg) in children ages 13 to 17 years 1 lb (0.4 kg) in children ages 6 to 12 years To learn about weight loss in adults who took Vyvanse for binge eating disorder, see the drugs prescribing information
It contains the active ingredient semaglutide, which is the same as the weight loss injection Wegovy
A 2026 UK evidence review of the maternal brain remodelling shown by Hoekzema 2017 and Pritschet 2024, the Davies 2018 cognition meta-analysis, the postpartum estradiol-BDNF crash, allopregnanolone and zuranolone, sleep, thyroid and iron drivers and why pregnancy and breastfeeding are absolute contraindications Read the full review Neuroscience 1 June 2026 Dihexa for Endometriosis Brain Fog & Endo-Associated Cognitive Dysfunction: The 2026 UK Review Rigorous 2026 UK review of Dihexa for endometriosis brain fog and endometriosis-associated cognitive dysfunction
Women using oral contraceptives should use a backup method for 4 weeks after initiating tirzepatide and after each dose increase due to potential delayed absorption
Concentration changes between refills are the single most common cause of unintentional dose errors in compounded GLP-1 therapy (Nguyen et al., Journal of Managed Care Pharmacy , 2025)