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Its primarily used for diabetes but has gained popularity for weight loss as well. Zepbound, which uses the same active ingredient as Mounjaro but is approved for weight loss, costs about $1,000 per fill without insurance. The cost of compounded semaglutide can vary based on the pharmacy and formulation

If youre taking Zepbound (tirzepatide), Ozempic (semaglutide), or any other GLP-1/GIP medication for weight loss, you may notice a change in your menstrual cycle due to several reasons

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In vivo, it is secreted by the L-cells of the small intestine in response to nutrient ingestion

Important safety considerations include a boxed warning for thyroid C-cell tumors, contraindication in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and precautions regarding pregnancy (not recommended), reduced oral contraceptive effectiveness, and risks of pancreatitis, gallbladder disease, and acute kidney injury