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The peptide demonstrates the unique ability to modulate pineal gland function, restoring the natural circadian production of melatonin that declines with age

Although FOXO4s specific effects on mitochondria are as direct as the other peptides above, it is known to regulate the expression of genes involved in oxidative stress response and energy metabolism, which can impact mitochondrial function indirectly (Liu, 2019)

In addition, ferroptosis is hypothesized to depend on intracellular iron concentration (8)

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