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All cells were cultured in a 5% CO 2 incubator at 37 C

A moderate exercise intensity was adopted, with the intensity range of 64-77% (HRmax = 207 0.7*9.9 = 200.03, HRmax(64) = 200.03*0.64 = 128.19, HRmax (77) = 200.03*0.77 = 154.231)

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For each study, Cohens d was derived from the difference between pre- and post-intervention mean scores, divided by the pooled standard deviation (SD) of the pre- and post-intervention values

Researchers describe the cumulative toll of sustained activation as allostatic load, the wear and tear that may build when the body keeps adapting to unresolved stress