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The broader Spartan research library covers the GH/IGF axis in more detail across multiple compound entries
This is unexpected because GLP-1 normally helps lower blood sugar, slow digestion, and reduce appetite
GI side effects affect 10% to 40% of GLP-1 users, particularly during the first few weeks and during each dose escalation
Second, different chemical structures, pharmacological profiles, and modes of action of these GLP-1RA are available, and although the differences are subtle, head-to-head cardiovascular outcomes trials for this class of drugs are not available, which limits the ability to detect differences in outcomes between GLP-1 agonists of different structures or potencies and to rule out whether they affect treatment outcomes
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