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Transcribed image text: Problem 2: N-acetyl para-benzoquinone (NAPQI) is an oxidized metabolite of acetaminophen formed in the liver
L-arginine is utilized in the synthesis of nitric oxide by NOS3
Human trials showed that in people with high-risk features, treatment with minocycline reduced in 6 months the risk of conversion to MS, decreased lesion volume, and showed the absence of new enhancing lesions, but this effect did not last beyond 24 months of study (Preiningerova et al., 2022)
As the presented experiments do not report absolute changes in alcohol drinking after GLP-1R agonist treatment, the effectiveness of the different agonists cannot be compared
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