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Significant sodium abnormalities, for example, could theoretically lower seizure threshold, though this would be an indirect rather than direct drug effect

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Koch A, Konig B, Luci S, Stangl GI, Eder K: Dietary oxidised fat up regulates the expression of organic cation transporters in liver and small intestine and alters carnitine concentrations in liver, muscle and plasma of rats

Certain Bifidobacterium and Lactobacillus species can produce GABA 296,297,298,299,300 , and oral treatment with GABA or bacteria that produce GABA improves metabolic parameters in mice 298,301

doi: 10.1016/0006-8993(89)90498-8