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Metabolic regulation: NAD+ influences insulin sensitivity, fat oxidation, and glucose homeostasis through its role in metabolic enzyme reactions
Kaye AD, Allen KE, Smith Iii VS, Tong VT, Mire VE, Nguyen H, Lee Z, Kouri M, Jean Baptiste C, Mosieri CN, Kaye AM, Varrassi G, Shekoohi S
Epitalon mechanism is better understood at the enzymatic level (AANAT upregulation, pCREB activation) but the full picture of how it achieves tissue-specific pineal protection remains unclear