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Compounded Tirzepatide is the only medication on the market that can imitate both the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), hormones, which are naturally released into your digestive system when you eat
This dual action means tirzepatide doesn't just push out more insulin
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The Increlex (mecasermin) FDA label, which covers native rhIGF-1 in pediatric severe primary IGFD, is the closest human reference and informs the contraindications below
doi:10.1111/dom.13820 Leslie RD, Cohen RM
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