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Patients with certain GLP1R variants may achieve therapeutic benefit at lower doses, while others require higher exposure for equivalent weight lossand mismatched dosing in either direction increases overdose or inefficacy risk
Eur J Pain 2009;13(5):492-496
Clinical trials of Ozempic showed a decrease in haemoglobin A1C, which is a measure of blood sugar control, by 1% in 3 months [5]
One study proposed a drug response prediction method based on graph neural networks (GNN), which can integrate drug molecular graphs and gene expression data to predict the response of cancer cells to drugs and reveal their mechanisms of action [186]
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