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The pathogenesis of BPD is multifactorial, but pulmonary injury secondary to oxygen free radical production and inflammation form an important common pathway leading to altered lung development 2, 3
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Research has shown that circulating IL-8 levels are markedly increased in patients with severe AH, serving as superior indicators of short-term mortality compared to traditional prognostic markers [136]
Conclusions were drawn by considering the consistency of findings across studies and giving greater weight to evidence derived from human clinical investigations whenever available
