This is where liposomal technology steps in and changes the game
Additionally, case reports and prospective cohort studies of patients treated with GLP-1 RAs have demonstrated reductions in the Psoriasis Area and Severity Index (PASI) score, Physicians Global Assessment (PGA), and Dermatology Life Quality Index (DLQI) after 212 months of treatment [11,12,13,14,15,16]
Translating a 15 mg/kg murine dose directly to humans underscores a severe translational gap in the source paper
Patients with lighter skin types generally require a longer loading phase, while those with naturally olive or medium-toned skin may respond faster
Otherwise, current recommendations are for patients to be screened for baseline diabetic retinopathy before initiating GLP-1RA and participate in personalized risk discussions