Supplements should target a demonstrated deficiency or a clinically credible risk, with appropriate monitoring
Although different GLP-1 medications use different technologies, they all work by targeting the same biological pathway
Design In the obesity trial, 338 participants (mean age 48 years, 48% women, mean BMI 37.3 kg/m 2 ) were randomised (2:1:1:1:1:2:2) to retatrutide 1 mg, 4 mg (titration), 4 mg (no titration), 8 mg (slow titration), 8 mg (fast titration), 12 mg or placebo over 48 weeks [45]
The clinical trial evidence on duration The landmark STEP trials for semaglutide and SURMOUNT trials for tirzepatide provide the clearest data on what happens at different treatment durations
Margaret no problem with this product, i have lost 6 pounds so far in 3 weeks