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Oxidative stress is closely associated with inflammation
The observations during the baseball game travel suggested that the hypobaric/hypoxic stress induced by road travel through Eisenhower Tunnel (0.66 ATA) on the patient's dementia (22, 23), a 0.13 ATA decrease in pressure and oxygen pressure, was similar to Cunningham's observations of Spanish flu patients in the Rocky Mountains (6)
65 Mice homozygous for the physiologically important AKT substrate TBC1D4 Thr 649 knock-in exhibit impaired insulin-stimulated myocellular GLUT4 translocation and induction of glucose intolerance
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Nature 450 , 110114 (2007)
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