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Of potential significance to diabetes is that these effects in pancreatic -beta cells leads to decreased insulin secretion

Using Z79.4 tells a more complete story: not just that a patient has diabetes, but that they are on chronic insulin therapy, which may affect care planning, lab monitoring, and patient education

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This profile supports its application in research focused on alternative pain signaling mechanisms, including interactions with endogenous opioid peptides and neurochemical mediators such as substance P