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Traditional hormonal avenues of treatment are also explored with repurposed medicines, like progestogens (two), GnRH antagonists (one) and other gynaecological medications such as fezolinetant, marketed for treatment of menopause related vasomotor symptoms (in Phase II), and three drugs initially developed for treating breast cancer (tamoxifen, raloxifene, letrozole)

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Fat cells release estrogen, so the more a person gains, the more estrogen theyll have, Shah said

All patients were initially evaluated and diagnosed with BMS according to the diagnostic criteria defined by the International Classification of Headache Disorders, 3rd edition (ICHD-III) 22