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Discovery and Characterization Pickart and Thaler (1973) first isolated GHK from human plasma and characterized its copper-binding properties

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Moreover, the level of mitochondrial DNA 8-hydroxydeoxyguanosine in peripheral blood mononuclear cells from people with HIV correlates with HIV-related structural brain changes seen by magnetic resonance imaging of the brain: lateral ventricular enlargement and decreased volumes of the hippocampus, pallidum, and total subcortical gray matter 31

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