Clinical safety and efficacy in humans have not been established
Case in point, 7 days of L-citrulline supplementation at a daily dose of 6 g significantly increase plasma citrulline, arginine, and nitrite levels, VO 2 kinetics, in response to moderate intensity (70% VO 2 peak) exercise performance [18]
There are several studies suggesting that neutrophils have the ability to phagocytose various viruses, including Influenza , Cytomegalovirus, and Herpes simplex viruses [20,21,22,23,24]
Active or past cancer, pregnancy or breastfeeding, or uncontrolled diabetes
This is the part that surprises people